Doxoves® - PEGylated Liposomal Doxorubicin HCl (2.0mg/mL)
Doxorubicin HCl is loaded into PEGylated liposomes with ammonium gradient by the active loading approach to 2.0mg/mL drug concentration. The liposomes are prepared to high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency. Note we also carry a high drug concentration (4.0 mg/mL) version of this product (F30204B). Control liposomes for this product: F30204B-C2
For preclinical research in animal models only. Not for veterinary or human use
Orders are only accepted from verified institutional, academic, or corporate laboratory addresses. We do not ship to individuals or residential addresses
Specifications
Product code: F30204B-D2
Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol)
Lipid concentration: 20.0 mM
Doxorubicin HCl: 2.0 mg/mL
Encapsulation efficiency: > 95% (typically 98%)
Loading battery: 250 mM ammonium sulfate
Mean particle size: 85 nm (80 - 90 nm)
External solution: 10% sucrose, 10 mM histidine, pH 6.5
Shelf-life: 6 months, storage: 2-8 degree C
HSPC: hydrogenated phosphatidylcholine (Soy)
CHOL: cholesterol
mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]
