DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Gradient (100nm)
This product is prepared to the finest quality and shipped to you ready for drug loading. DSPC/CHO liposomes with ammonium gradient is the formulator's choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C)
One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain DSPC liposomes as placebo control (F10203)
Specifications
Product code: F20103A
Lipid composition: DSPC/CHOL (55:45 mol/mol)
Mean particle size: 100 nm (95 - 120 nm)
Lipid concentration: 60 mM (60 - 70 mM)
Hydration buffer (loading battery): 250 mM ammonium sulfate
External solution: 10% sucrose, 20mM NaPO4, pH 6.5 ± 0.2
Shelf-life: 6 months
Storage: 2-8 °C
DSPC: 18:0 PC,1,2-distearoyl-sn-glycero-3-phosphocholine
CHOL: cholesterol