Alenphosome™-A - Alendronate Liposomes (Anionic)
Specifications
Active: alendronate sodium (CAS 121268-17-5), 5.0 mg/mL
Volume: 2.0 mL
Lipid composition: phosphatidylcholine, phosphatidylglycerol and cholesterol
Internal/External solution: phosphate buffered saline (20mM sodium phosphate, 09wt% NaCl), pH 7.0 - 7.5
Usage: warm to room temperature and mix well before use.
Dosage: this is a new product and no recommended dose is available at this point. Refer the following literature for additional information
References
Benjamin J. Burwitz et al. Technical Advance: Liposomal alendronate depletes monocytes and macrophages in the nonhuman primate model of human disease. J Leukoc Biol. 2014 Sep; 96(3): 491–501. PMC4632165 (Link)
Renate Frei, Comparison of cytotoxic properties of free and liposomal bisphosphonates in vitro (Diploma Thesis) (Link)