PROUD PROVIDER OF LIPOSOME PRODUCTS AND FORMULATION SERVICES

Analytical and Characterization

Formulation Physical Characterization
  • Particle size and distribution by DLS (Brookhaven ZetaPALS)
  • Zeta Potential and Mobility (Brookhaven ZetaPALS)
  • Particle size, distribution and particle concentration by qNano (directly measures the properties of individual nanoparticles in solution)
  • Drug encapsulation efficiency (free drug separated and assayed by HPLC or other analytical means)
  • Lipid/liposome phase transition, enthalpy (MicoCal VP-DSC)
  • Polymer glass transition, melting point (Perkin Elmer DSC 7)
  • Lyophylization/Freeze trying (Virtis Genesis)
  • Formulation examination under microscope

Analytical Sciences
  • HPLC method development (Agilent 1100 HPLC, Waters 2695)
  • HPLC measurement of drug potency and degradents
  • Lipid assay
  • Drug assay (HPLC, UV SpectraMax plate reader, SpectraMax Gemini XS plate reader)
  • Formulation stability (chemical and physical)
  • Lipid/liposome phase transition, enthalpy (MicoCal VP-DSC)
  • Polymer glass transition, melting point (Perkin Elmer DSC 7)
  • In vitro drug release assay
  • pH
  • Osmolarity (Wescor Vapro Osmometer 5520 and OSMETTE XL™ 5007 )
  • Viscosity (Brookfield DV-II+Pro)
  • Refractive Index

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