Publications on Clophosome® (Neutral)

Publications on Clophosome® (the neutral clodronate liposomes through 04/27/2019)

 

M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes

Li Bai, Xin Liu, Qingfen Zheng, Ming Kong, Xiaohui Zhang, Richard Hu, Jinli Lou, Feng Ren, Yu Chen, Sujun Zheng, Shuang Liu, Yuan-Ping Han, Zhongping Duan, Stephen J. Pandol. Sci Rep. 2017; 7: 10518. Published online 2017 Sep 5

 

FicolinA/2, acting as a new regulator of macrophage polarization, mediates the inflammatory response in experimental mouse colitis

YiFei Yang, YiDan Zhou, JiaChen Hu, FengLing Luo, Yan Xie, YanYing Shen, WenXiu Bian, ZhiNan Yin, HongLiang Li, XiaoLian Zhang

Immunology. 2017 Aug; 151(4): 433–450. Published online 2017 May 15

 

Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression

Ruihua Ma, Tiantian Ji, Degao Chen, Wenqian Dong, Huafeng Zhang, Xiaonan Yin, Jingwei Ma, Xiaoyu Liang, Yi Zhang, Guanxin Shen, Xiaofeng Qin, Bo Huang

Oncoimmunology. 2016 Apr; 5(4): e1118599. Published online 2016 Feb 18

 

Combined Rho-kinase inhibition and immunogenic cell death triggers and propagates immunity against cancer

Gi-Hoon Nam, Eun Jung Lee, Yoon Kyoung Kim, Yeonsun Hong, Yoonjeong Choi, Myung-Jeom Ryu, Jiwan Woo, Yakdol Cho, Dong June Ahn, Yoosoo Yang, Ick-Chan Kwon, Seung-Yoon Park, In-San Kim

Nat Commun. 2018; 9: 2165. Published online 2018 Jun 4. 

 

Colchicine alleviates acute postoperative pain but delays wound repair in mice: Roles of neutrophils and macrophages

Asami Sukeishi, Koichi Isami, Haruka Hiyama, Satoshi Imai, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kaneko

Mol Pain. 2017; 13: 1744806917743680. Published online 2017 Nov 7.

 

Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles

Yu Sakurai, Tomoya Hada, Shoshiro Yamamoto, Akari Kato, Wataru Mizumura, Hideyoshi Harashima

Mol Ther. 2016 Dec; 24(12): 2090–2099. Prepublished online 2016 Sep 16. 

 

Macrophage Depletion Protects against Cigarette Smoke-Induced Inflammatory Response in the Mouse Colon and Lung

Dahae Lim, Woogyeong Kim, Chanju Lee, Hyunsu Bae, Jinju Kim

Front Physiol. 2018; 9: 47. Published online 2018 Feb 12. 

 

Angiopoietin-like protein 2 facilitates non-small cell lung cancer progression by promoting the polarization of M2 tumor-associated macrophages

Xiaojuan Wei, Siyue Nie, Hui Liu, Jingyu Sun, Jie Liu, Juan Li, Shuyan Li, Shuyun Wang, Shuyi Han, Jun Wang, Yuping Sun

Am J Cancer Res. 2017; 7(11): 2220–2233. Published online 2017 Nov 1.

 

Arginase1 deficiency in monocytes/macrophages up-regulates iNOS to promote cutaneous contact hypersensitivity

Jutamas Suwanpradid, Michael Shih, Lauren Pontius, Bin Yang, Anastasiya Birukova, Emma Guttman-Yasky, David L. Corcoran, Loretta G. Que, Robert M. Tighe, Amanda S. MacLeod

J Immunol. Author manuscript; available in PMC 2018 Sep 1.

Published in final edited form as: J Immunol. 2017 Sep 1; 199(5): 1827–1834. Published online 2017 Jul 26. 

 

Age-Dependent Myeloid Dendritic Cell Responses Mediate Resistance to La Crosse Virus-Induced Neurological Disease

Katherine G. Taylor, Tyson A. Woods, Clayton W. Winkler, Aaron B. Carmody, Karin E. Peterson

J Virol. 2014 Oct; 88(19): 11070–11079. 

 

Mesenchymal stem cells ameliorate rhabdomyolysis-induced acute kidney injury via the activation of M2 macrophages

Yanqiu Geng, Li Zhang, Bo Fu, Jianrong Zhang, Quan Hong, Jie Hu, Diangeng Li, Congjuan Luo, Shaoyuan Cui, Fei Zhu, Xiangmei Chen

Stem Cell Res Ther. 2014; 5(3): 80. Published online 2014 Jun 24. 

 

Choroidal Neovascularization Is Inhibited in Splenic-Denervated or Splenectomized Mice with a Concomitant Decrease in Intraocular Macrophage

Xue Tan, Katsuhito Fujiu, Ichiro Manabe, Junko Nishida, Reiko Yamagishi, Yuya Terashima, Kouji Matsushima, Toshikatsu Kaburaki, Ryozo Nagai, Yasuo Yanagi

PLoS One. 2016; 11(8): e0160985. Published online 2016 Aug 17. 

 

Skeletal callus formation is a nerveindependent regenerative response to limb amputation in mice and Xenopus

Shinichirou Miura, Yumiko Takahashi, Akira Satoh, Tetsuya Endo

Regeneration (Oxf) 2015 Aug; 2(4): 202–216. Published online 2015 Aug 26. 

 

Alveolar Macrophages Treated With Bacillus subtilis Spore Protect Mice Infected With Respiratory Syncytial Virus A2

Ji Eun Hong, Yoon-Chul Kye, Sung-Moo Park, In Su Cheon, Hyuk Chu, Byung-Chul Park, Yeong-Min Park, Jun Chang, Jae-Ho Cho, Man Ki Song, Seung Hyun Han, Cheol-Heui Yun

Front Microbiol. 2019; 10: 447. Published online 2019 Mar 12. 

 

Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

Qinglei Gao, Zongyuan Yang, Sen Xu, Xiaoting Li, Xin Yang, Ping Jin, Yi Liu, Xiaoshui Zhou, Taoran Zhang, Cheng Gong, Xiao Wei, Dan Liu, Chaoyang Sun, Gang Chen, Junbo Hu, Li Meng, Jianfeng Zhou, Kenjiro Sawada, Robert Fruscio, Thomas W. Grunt, Jörg Wischhusen, Víctor Manuel Vargas-Hernández, Bhavana Pothuri, Robert L. Coleman

J Exp Med. 2019 Mar 4; 216(3): 688–703. 

 

LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats

Jianhua Peng, Jinwei Pang, Lei Huang, Budbazar Enkhjargal, Tongyu Zhang, Jun Mo, Pei Wu, Weilin Xu, Yuchun Zuo, Jun Peng, Gang Zuo, Ligang Chen, Jiping Tang, John H. Zhang, Yong Jiang

Redox Biol. 2019 Feb; 21: 101121. Published online 2019 Jan 23. 

 

Involvement of M1 Macrophage Polarization in Endosomal Toll-Like Receptors Activated Psoriatic Inflammation

Chih-Hao Lu, Chao-Yang Lai, Da-Wei Yeh, Yi-Ling Liu, Yu-Wen Su, Li-Chung Hsu, Chung-Hsing Chang, S.-L. Catherine Jin, Tsung-Hsien Chuang

Mediators Inflamm. 2018; 2018: 3523642. Published online 2018 Dec 16. 

 

RAMP1 in Kupffer cells is a critical regulator in immune-mediated hepatitis

Tomoyoshi Inoue, Yoshiya Ito, Nobuyuki Nishizawa, Koji Eshima, Ken Kojo, Fumisato Otaka, Tomohiro Betto, Sakiko Yamane, Kazutake Tsujikawa, Wasaburo Koizumi, Masataka Majima

PLoS One. 2018; 13(11): e0200432. Published online 2018 Nov 21. 

 

Kidney-resident macrophages promote a proangiogenic environment in the normal and chronically ischemic mouse kidney

Amrutesh S. Puranik, Irina A. Leaf, Mark A. Jensen, Ahmad F. Hedayat, Ahmad Saad, Ki-Wook Kim, Abdulrahman M. Saadalla, John R. Woollard, Sonu Kashyap, Stephen C. Textor, Joseph P. Grande, Amir Lerman, Robert D. Simari, Gwendalyn J. Randolph, Jeremy S. Duffield, Lilach O. Lerman

Sci Rep. 2018; 8: 13948. Published online 2018 Sep 17. 

 

USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation

Chih-Hao Lu, Da-Wei Yeh, Chao-Yang Lai, Yi-Ling Liu, Li-Rung Huang, Alan Yueh-Luen Lee, S.-L. Catherine Jin, Tsung-Hsien Chuang

Oncogene. 2018; 37(49): 6327–6340. Published online 2018 Jul 23. 

 

Brown adipose tissue plays a central role in systemic inflammation-induced sleep responses

Éva Szentirmai, Levente Kapás

PLoS One. 2018; 13(5): e0197409. Published online 2018 May 10. 

 

Neuropeptide regulation of adaptive immunity in the tibia fracture model of complex regional pain syndrome

Wen-Wu Li, Tian-Zhi Guo, Xiaoyou Shi, Frank Birklein, Tanja Schlereth, Wade S. Kingery, J. David Clark

J Neuroinflammation. 2018; 15: 105. Published online 2018 Apr 11. 

 

Detrimental Influence of Alveolar Macrophages on Protective Humoral Immunity during Francisella tularensis SchuS4 Pulmonary Infection

Donald J. Steiner, Yoichi Furuya, Dennis W. Metzger

Infect Immun. 2018 Apr; 86(4): e00787-17. Prepublished online 2018 Jan 8. Published online 2018 Mar 22. 

 

Splenic leukocytes define the resolution of inflammation in heart failure

Ganesh V. Halade, Paul C. Norris, Vasundhara Kain, Charles N. Serhan, Kevin A. Ingle

Sci Signal. 2018 Mar 6; 11(520): eaao1818. Published online 2018 Mar 6. 

 

Reverse Engineering the Intracellular Self-Assembly of a Functional Mechanopharmaceutical Device

Tehetina Woldemichael, Rahul K. Keswani, Phillip M. Rzeczycki, Mikhail D. Murashov, Vernon LaLone, Brian Gregorka, Joel A. Swanson, Kathleen A. Stringer, Gus R. Rosania

Sci Rep. 2018; 8: 2934. Published online 2018 Feb 13. 

 

Tumor-derived thymic stromal lymphopoietin enhances lung metastasis through an alveolar macrophage-dependent mechanism

Lauren Burkard-Mandel, Rachel O'Neill, Sean Colligan, Mukund Seshadri, Scott I. Abrams

Oncoimmunology. 2018; 7(5): e1419115. Published online 2018 Jan 16. 

 

Elimination of tumor by CD47/PD-L1 dual-targeting fusion protein that engages innate and adaptive immune responses

Boning Liu, Huaizu Guo, Jin Xu, Ting Qin, Qingcheng Guo, Nana Gu, Dapeng Zhang, Weizhu Qian, Jianxin Dai, Sheng Hou, Hao Wang, Yajun Guo

MAbs. 2018 Feb-Mar; 10(2): 315–324. Published online 2017 Dec 20. 

 

Hepatic recruitment of CD11b+Ly6C+ inflammatory monocytes promotes hepatic ischemia/reperfusion injury

Peng Song, Junbin Zhang, Yunwei Zhang, Zhiping Shu, Peng Xu, Long He, Chao Yang, Jinxiang Zhang, Hui Wang, Yiqing Li, Qin Li

Int J Mol Med. 2018 Feb; 41(2): 935–945. Published online 2017 Dec 8. 

 

Levels of S100B protein drive the reparative process in acute muscle injury and muscular dystrophy

Francesca Riuzzi, Sara Beccafico, Roberta Sagheddu, Sara Chiappalupi, Ileana Giambanco, Oxana Bereshchenko, Carlo Riccardi, Guglielmo Sorci, Rosario Donato

Sci Rep. 2017; 7: 12537. Published online 2017 Oct 2. 

 

Sestrin2 Suppresses Classically Activated Macrophages-Mediated Inflammatory Response in Myocardial Infarction through Inhibition of mTORC1 Signaling

Keping Yang, Chenhong Xu, Yunfeng Zhang, Shaolin He, Dazhu Li

Front Immunol. 2017; 8: 728. Published online 2017 Jun 30. 

 

Aging impairs alveolar macrophage phagocytosis and increases influenza-induced mortality in mice

Christine K. Wong, Candice A. Smith, Koji Sakamoto, Naftali Kaminski, Jonathan L. Koff, Daniel R. Goldstein

J Immunol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: J Immunol. 2017 Aug 1; 199(3): 1060–1068. Published online 2017 Jun 23. 

 

IL33 Promotes Colon Cancer Cell Stemness via JNK Activation and Macrophage Recruitment

Min Fang, Yongkui Li, Kai Huang, Shanshan Qi, Jian Zhang, Witold Zgodzinski, Marek Majewski, Grzegorz Wallner, Stanislaw Gozdz, Pawel Macek, Artur Kowalik, Marcin Pasiarski, Ewelina Grywalska, Linda Vatan, Nisha Nagarsheth, Wei Li, Lili Zhao, Ilona Kryczek, Guobin Wang, Zheng Wang, Weiping Zou, Lin Wang

Cancer Res. Author manuscript; available in PMC 2018 Jan 9.

Published in final edited form as: Cancer Res. 2017 May 15; 77(10): 2735–2745. Published online 2017 Mar 1. 

 

Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling

Wei Ying, Joshua Wollam, Jachelle M. Ofrecio, Gautam Bandyopadhyay, Dalila El Ouarrat, Yun Sok Lee, Da Young Oh, Pingping Li, Olivia Osborn, Jerrold M. Olefsky

J Clin Invest. 2017 Mar 1; 127(3): 1019–1030. Published online 2017 Feb 13. 

 

Macrophage Colony Stimulating Factor Derived from CD4+ T Cells Contributes to Control of a Blood-Borne Infection

Mary F. Fontana, Gabrielly L. de Melo, Chioma Anidi, Rebecca Hamburger, Chris Y. Kim, So Youn Lee, Jennifer Pham, Charles C. Kim

PLoS Pathog. 2016 Dec; 12(12): e1006046. Published online 2016 Dec 6. 

 

Interleukin23 Secreted by Activated Macrophages Drives γδT Cell Production of Interleukin17 to Aggravate Secondary Injury After Intracerebral Hemorrhage

Qi Zhong, Kai Zhou, QiaoLi Liang, Sen Lin, YanChun Wang, XiaoYi Xiong, ZhaoYou Meng, Ting Zhao, WenYao Zhu, YuanRui Yang, MaoFan Liao, QiuWen Gong, Liang Liu, Ao Xiong, Junwei Hao, Jian Wang, QingWu Yang

J Am Heart Assoc. 2016 Oct; 5(10): e004340. Published online 2016 Oct 11. 

 

Hypothalamic TLR2 triggers sickness behavior via a microglia-neuronal axis

Sungho Jin, Jae Geun Kim, Jeong Woo Park, Marco Koch, Tamas L. Horvath, Byung Ju Lee

Sci Rep. 2016; 6: 29424. Published online 2016 Jul 12. 

 

Critical role of the C5a-activated neutrophils in high-fat diet-induced vascular inflammation

Mizuko Osaka, Shunsuke Ito, Masaki Honda, Yukihiro Inomata, Kensuke Egashira, Masayuki Yoshida

Sci Rep. 2016; 6: 21391. Published online 2016 Feb 19.

 

Macrophage depletion by clodronate liposome attenuates muscle injury and inflammation following exhaustive exercise

Noriaki Kawanishi, Tsubasa Mizokami, Hiroyuki Niihara, Koichi Yada, Katsuhiko Suzuki

Biochem Biophys Rep. 2016 Mar; 5: 146–151. Published online 2015 Dec 4. 

 

Monocyte-derived extracellular Nampt-dependent biosynthesis of NAD+ protects the heart against pressure overload

Masamichi Yano, Hiroshi Akazawa, Toru Oka, Chizuru Yabumoto, Yoko Kudo-Sakamoto, Takehiro Kamo, Yu Shimizu, Hiroki Yagi, Atsuhiko T. Naito, Jong-Kook Lee, Jun-ichi Suzuki, Yasushi Sakata, Issei Komuro

Sci Rep. 2015; 5: 15857. Published online 2015 Nov 2. 

 

Protective Efficacy and Mechanism of Passive Immunization with Polyclonal Antibodies in a Sepsis Model of Staphylococcus aureus Infection

Jinyong Zhang, Feng Yang, Xiaoli Zhang, Haiming Jing, Chunyan Ren, Changzhi Cai, Yandong Dong, Yudong Zhang, Quanming Zou, Hao Zeng

Sci Rep. 2015; 5: 15553. Published online 2015 Oct 22. 

 

IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs

Satoshi Nishimura, Mika Nagasaki, Shinji Kunishima, Akira Sawaguchi, Asuka Sakata, Hiroyasu Sakaguchi, Tsukasa Ohmori, Ichiro Manabe, Joseph E. Italiano, Jr., Tomiko Ryu, Naoya Takayama, Issei Komuro, Takashi Kadowaki, Koji Eto, Ryozo Nagai

J Cell Biol. 2015 May 11; 209(3): 453–466. 

 

Corneal lymphangiogenesis ameliorates corneal inflammation and edema in late stage of bacterial keratitis

Akitomo Narimatsu, Takaaki Hattori, Naohito Koike, Kazuki Tajima, Hayate Nakagawa, Naoyuki Yamakawa, Yoshihiko Usui, Shigeto Kumakura, Tetsuya Matsumoto, Hiroshi Goto

Sci Rep. 2019; 9: 2984. Published online 2019 Feb 27. 

 

Interleukin-17 Induces an Atypical M2-Like Macrophage Subpopulation That Regulates Intestinal Inflammation

Kenichiro Nishikawa, Naohiro Seo, Mie Torii, Nei Ma, Daisuke Muraoka, Isao Tawara, Masahiro Masuya, Kyosuke Tanaka, Yoshiyuki Takei, Hiroshi Shiku, Naoyuki Katayama, Takuma Kato

PLoS One. 2014; 9(9): e108494. Published online 2014 Sep 25. 

 

Vagus-macrophage-hepatocyte link promotes post-injury liver regeneration and whole-body survival through hepatic FoxM1 activation

Tomohito Izumi, Junta Imai, Junpei Yamamoto, Yohei Kawana, Akira Endo, Hiroto Sugawara, Masato Kohata, Yoichiro Asai, Kei Takahashi, Shinjiro Kodama, Keizo Kaneko, Junhong Gao, Kenji Uno, Shojiro Sawada, Vladimir V. Kalinichenko, Yasushi Ishigaki, Tetsuya Yamada, Hideki Katagiri

Nat Commun. 2018; 9: 5300. Published online 2018 Dec 13. 

 

Intestinal barrier regulates immune responses in the liver via IL-10–producing macrophages

Nobuhito Taniki, Nobuhiro Nakamoto, Po-Sung Chu, Yohei Mikami, Takeru Amiya, Toshiaki Teratani, Takahiro Suzuki, Tomoya Tsukimi, Shinji Fukuda, Akihiro Yamaguchi, Shunsuke Shiba, Rei Miyake, Tadashi Katayama, Hirotoshi Ebinuma, Takanori Kanai

JCI Insight. 2018 Jun 21; 3(12): e91980. Published online 2018 Jun 21. 

 

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype

Degao Chen, Jing Xie, Roland Fiskesund, Wenqian Dong, Xiaoyu Liang, Jiadi Lv, Xun Jin, Jinyan Liu, Siqi Mo, Tianzhen Zhang, Feiran Cheng, Yabo Zhou, Huafeng Zhang, Ke Tang, Jingwei Ma, Yuying Liu, Bo Huang

Nat Commun. 2018; 9: 873. Published online 2018 Feb 28. 

 

Kupffer cell-derived TNF-α promotes hepatocytes to produce CXCL1 and mobilize neutrophils in response to necrotic cells

Li Su, Na Li, Hua Tang, Ziyang Lou, Xiaodan Chong, Chenxi Zhang, Jiacan Su, Xin Dong

Cell Death Dis. 2018 Mar; 9(3): 323. Published online 2018 Feb 23. 

 

Toll-Like Receptor 4 Agonistic Antibody Promotes Innate Immunity against Severe Pneumonia Induced by Coinfection with Influenza Virus and Streptococcus pneumoniae

Akitaka Tanaka, Shigeki Nakamura, Masafumi Seki, Kenji Fukudome, Naoki Iwanaga, Yoshifumi Imamura, Taiga Miyazaki, Koichi Izumikawa, Hiroshi Kakeya, Katsunori Yanagihara, Shigeru Kohno

Clin Vaccine Immunol. 2013 Jul; 20(7): 977–985. 

 

Macrophage scavenger receptor 1 contributes to pathogenesis of fulminant hepatitis via neutrophil-mediated complement activation

Yuan Tang, Huifang Li, Junru Li, Yunzhi Liu, Yanli Li, Jing Zhou, Jia Zhou, Xiao Lu, Wei Zhao, Jinlin Hou, Xiang-Yang Wang, Zhengliang Chen, Daming Zuo

J Hepatol. 2018 Apr; 68(4): 733–743. Published online 2017 Nov 14. 

 

Angiotensin II subtype 1a receptor signaling in resident hepatic macrophages induces liver metastasis formation

Yuki Shimizu, Hideki Amano, Yoshiya Ito, Tomohiro Betto, Sakiko Yamane, Tomoyoshi Inoue, Nobuyuki Nishizawa, Yoshio Matsui, Mariko Kamata, Masaki Nakamura, Hidero Kitasato, Wasaburo Koizumi, Masataka Majima

Cancer Sci. 2017 Sep; 108(9): 1757–1768. Published online 2017 Jul 27. 

 

A Natural CCR2 Antagonist Relieves Tumor-associated Macrophage-mediated Immunosuppression to Produce a Therapeutic Effect for Liver Cancer

Wenbo Yao, Qian Ba, Xiaoguang Li, Huiliang Li, Shoude Zhang, Ya Yuan, Feng Wang, Xiaohua Duan, Jingquan Li, Weidong Zhang, Hui Wang

EBioMedicine. 2017 Aug; 22: 58–67. Published online 2017 Jul 18. 

 

Melittin suppresses tumor progression by regulating tumor-associated macrophages in a Lewis lung carcinoma mouse model

Chanju Lee, Sung-Joo S. Bae, Hwansoo Joo, Hyunsu Bae

Oncotarget. 2017 Aug 15; 8(33): 54951–54965. Published online 2017 Jun 27. 

 

Protective Role for Macrophages in Respiratory Francisella tularensis Infection

Donald J. Steiner, Yoichi Furuya, Michael B. Jordan, Dennis W. Metzger

Infect Immun. 2017 Jun; 85(6): e00064-17. Prepublished online 2017 Apr 3. Published online 2017 May 23. 

 

Converting lymphoma cells into potent antigen-presenting cells for interferon-induced tumor regression

Jing Liao, Yan Luan, Zhenhua Ren, Xiaojuan Liu, Diyuan Xue, Hairong Xu, Zhichen Sun, Kaiting Yang, Hua Peng, Yang-Xin Fu

Cancer Immunol Res. Author manuscript; available in PMC 2018 Jul 1.

Published in final edited form as: Cancer Immunol Res. 2017 Jul; 5(7): 560–570. Published online 2017 May 22. 

 

Macrophage-stimulated microRNA expression in mural cells promotes transplantation-induced neointima formation

Xiaotong Guo, Mengyao Sun, Chaochao Dai, Xun Zhang, Qihui Yin, Jiaqi Ling, Xinyue Li, Xiao Wu, Fan Jiang, Jianli Wang

Oncotarget. 2017 May 2; 8(18): 30100–30111. Published online 2017 Mar 16. 

 

Sustained inflammation after pericyte depletion induces irreversible blood-retina barrier breakdown

Shuntaro Ogura, Kaori Kurata, Yuki Hattori, Hiroshi Takase, Toshina Ishiguro-Oonuma, Yoonha Hwang, Soyeon Ahn, Inwon Park, Wataru Ikeda, Sentaro Kusuhara, Yoko Fukushima, Hiromi Nara, Hideto Sakai, Takashi Fujiwara, Jun Matsushita, Masatsugu Ema, Masanori Hirashima, Takashi Minami, Masabumi Shibuya, Nobuyuki Takakura, Pilhan Kim, Takaki Miyata, Yuichiro Ogura, Akiyoshi Uemura

JCI Insight. 2017 Feb 9; 2(3): e90905. Published online 2017 Feb 9. 

 

Pericytes and immune cells contribute to complement activation in tubulointerstitial fibrosis

Sandhya Xavier, Ranjit K. Sahu, Susan G. Landes, Jing Yu, Ronald P. Taylor, Srinivas Ayyadevara, Judit Megyesi, William B. Stallcup, Jeremy S. Duffield, Edimara S. Reis, John D. Lambris, Didier Portilla

Am J Physiol Renal Physiol. 2017 Mar 1; 312(3): F516–F532. Published online 2017 Jan 3. 

 

The innate immune receptor Dectin-2 mediates the phagocytosis of cancer cells by Kupffer cells for the suppression of liver metastasis

Yoshitaka Kimura, Asuka Inoue, Sho Hangai, Shinobu Saijo, Hideo Negishi, Junko Nishio, Sho Yamasaki, Yoichiro Iwakura, Hideyuki Yanai, Tadatsugu Taniguchi

Proc Natl Acad Sci U S A. 2016 Dec 6; 113(49): 14097–14102. Published online 2016 Nov 21. 

 

Adoptively transferred donor IL-17-producing CD4+ T cells augment, but IL-17 alleviates, acute graft-versus-host disease

Yifeng Cai, Shoubao Ma, Yuejun Liu, Huanle Gong, Qiao Cheng, Bo Hu, Yan Wu, Xiao Yu, Chen Dong, Kai Sun, Depei Wu, Haiyan Liu

Cell Mol Immunol. 2018 Mar; 15(3): 233–245. Published online 2016 Oct 17. 

 

Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer

Mingzhu Yin, Xia Li, Shu Tan, Huanjiao Jenny Zhou, Weidong Ji, Stefania Bellone, Xiaocao Xu, Haifeng Zhang, Alessandro D. Santin, Ge Lou, Wang Min

J Clin Invest. 2016 Nov 1; 126(11): 4157–4173. Published online 2016 Oct 10. 

 

Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing

Takuro Miyazaki, Kazuo Tonami, Shoji Hata, Toshihiro Aiuchi, Koji Ohnishi, Xiao-Feng Lei, Joo-ri Kim-Kaneyama, Motohiro Takeya, Hiroyuki Itabe, Hiroyuki Sorimachi, Hiroki Kurihara, Akira Miyazaki

J Clin Invest. 2016 Sep 1; 126(9): 3417–3432. Published online 2016 Aug 15. 

 

Effects of Macrophage Depletion on Sleep in Mice

Conner Ames, Erin Boland, Éva Szentirmai

PLoS One. 2016; 11(7): e0159812. Published online 2016 Jul 21. 

 

Microglia retard dengue virus-induced acute viral encephalitis

Tsung-Ting Tsai, Chia-Ling Chen, Yee-Shin Lin, Chih-Peng Chang, Cheng-Chieh Tsai, Yi-Lin Cheng, Chao-Ching Huang, Chien-Jung Ho, Yi-Chao Lee, Liang-Tzung Lin, Ming-Kai Jhan, Chiou-Feng Lin

Sci Rep. 2016; 6: 27670. Published online 2016 Jun 9. 

 

Chop Deficiency Protects Mice Against Bleomycin-induced Pulmonary Fibrosis by Attenuating M2 Macrophage Production

Yingying Yao, Yi Wang, Zhijun Zhang, Long He, Jianghui Zhu, Meng Zhang, Xiaoyu He, Zhenshun Cheng, Qilin Ao, Yong Cao, Ping Yang, Yunchao Su, Jianping Zhao, Shu Zhang, Qilin Yu, Qin Ning, Xudong Xiang, Weining Xiong, Cong-Yi Wang, Yongjian Xu

Mol Ther. 2016 May; 24(5): 915–925. Prepublished online 2016 Feb 17. Published online 2016 Mar 15. 

 

Chemical dampening of Ly6Chi monocytes in the periphery produces anti-depressant effects in mice

Xiao Zheng, Sijing Ma, An Kang, Mengqiu Wu, Lin Wang, Qiong Wang, Guangji Wang, Haiping Hao

Sci Rep. 2016; 6: 19406. Published online 2016 Jan 19. 

 

The role of erythrocyte CD47 in intracerebral hematoma clearance

Wei Ni, Shanshan Mao, Guohua Xi, Richard F. Keep, Ya Hua

Stroke. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Stroke. 2016 Feb; 47(2): 505–511. Published online 2016 Jan 5. 

 

Sphingosine 1-Phosphate Receptor 3–Deficient Dendritic Cells Modulate Splenic Responses to Ischemia-Reperfusion Injury

Amandeep Bajwa, Liping Huang, Elvira Kurmaeva, Joseph C. Gigliotti, Hong Ye, Jacqueline Miller, Diane L. Rosin, Peter I. Lobo, Mark D. Okusa

J Am Soc Nephrol. 2016 Apr; 27(4): 1076–1090. Published online 2015 Aug 18. 

 

Allergic Lung Inflammation Reduces Tissue Invasion and Enhances Survival from PulmonaryPneumococcal Infection in Mice, Which Correlates with Increased Expression of Transforming Growth Factor β1 and SiglecFlow Alveolar Macrophages

Alan M. Sanfilippo, Yoichi Furuya, Sean Roberts, Sharon L. Salmon, Dennis W. Metzger

Infect Immun. 2015 Jul; 83(7): 2976–2983. Prepublished online 2015 May 11. Published online 2015 Jun 15. 

 

Mechanisms of TNFα antagonist-induced lupus in a murine model

Yuan Xu, Haoyang Zhuang, Shuhong Han, Chao Liu, Hai Wang, Clayton E. Mathews, John Massini, Li-Jun Yang, Westley H. Reeves

Arthritis Rheumatol. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Arthritis Rheumatol. 2015 Jan; 67(1): 225–237. 

 

Upregulation of Stromal Cell–Derived Factor 1 (SDF-1) is Associated with Macrophage Infiltration in Renal Ischemia-Reperfusion Injury

Xin Wan, Wenkai Xia, Yasser Gendoo, Wen Chen, Wenjin Sun, Dong Sun, Changchun Cao

PLoS One. 2014; 9(12): e114564. Published online 2014 Dec 5. 

 

Spreading Depression Requires Microglia and is Decreased by their M2a Polarization from Environmental Enrichment

Kae M. Pusic, Aya D. Pusic, Jordan Kemme, Richard P. Kraig

Glia. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Glia. 2014 Jul; 62(7): 1176–1194. Published online 2014 Apr 10. 

 

Gut microbiota promotes hematopoiesis tocontrol bacterial infection

Arya Khosravi, Alberto Yáñez, Jeremy G. Price, Andrew Chow, Miriam Merad, Helen S. Goodridge, Sarkis K. Mazmanian

Cell Host Microbe. Author manuscript; available in PMC 2015 Mar 12.

Published in final edited form as: Cell Host Microbe. 2014 Mar 12; 15(3): 374–381. 

 

Longitudinal PET Imaging of Muscular Inflammation Using 18F-DPA-714 and 18F-Alfatide II and Differentiation with Tumors

Chenxi Wu, Xuyi Yue, Lixin Lang, Dale O. Kiesewetter, Fang Li, Zhaohui Zhu, Gang Niu, Xiaoyuan Chen

Theranostics. 2014; 4(5): 546–555. Published online 2014 Feb 26. 

 

Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma

Kai Song, Brett H. Herzog, Minjia Sheng, Jianxin Fu, J. Michael McDaniel, Jia Ruan, Lijun Xia

Cancer Res. Author manuscript; available in PMC 2014 Dec 15.

Published in final edited form as: Cancer Res. 2013 Dec 15; 73(24): 7254–7264. Published online 2013 Oct 24. 

 

CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice

Florian Sennlaub, Constance Auvynet, Bertrand Calippe, Sophie Lavalette, Lucie Poupel, Shulong J Hu, Elisa Dominguez, Serge Camelo, Olivier Levy, Elodie Guyon, Noah Saederup, Israel F Charo, Nico Van Rooijen, Emeline Nandrot, Jean-Louis Bourges, Francine Behar-Cohen, José-Alain Sahel, Xavier Guillonneau, William Raoul, Christophe Combadiere

EMBO Mol Med. 2013 Nov; 5(11): 1775–1793. Published online 2013 Oct 21. 

 

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental nonalcoholic steatohepatitis

Saurabh Chatterjee, Douglas Ganini, Erik J. Tokar, Ashutosh Kumar, Suvarthi Das, Jean Corbett, Maria Kadiiska, Michael Waalkes, Anna Mae Diehl, Ronald P. Mason

J Hepatol. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: J Hepatol. 2013 Apr; 58(4): 778–784. Published online 2012 Dec 1.