Services Offered

Formumax specializes in a variety of formulation and drug delivery technologies, including solubility enhancing liposome systems and advanced nano-enabled systems such as PEGylated liposomes (STEALTH liposomes), PEGylated lipospheres, and polymer-based nanoparticles for controlled and sustained delivery of various types of compounds. With over thirty years of experience, our team has strong expertise in the design and development of delivery systems, including drug carrier systems, drug loading and drug retention technologies. We offer formulation services and analytical support to the pharmaceutical and biotech industries.

• Custom liposomes tailored to your need

• Plain liposomes

• Fluorescent liposomes

• Cationic liposomes

• liposomes with functional groups

• Targeted liposomes

• Lipid-nanoparticles for DNA, mRNA and siRNA

• Formulation feasibility studies and prototype development

• Passive loading for soluble and insoluble compounds

• Active loading for special compounds

• Cationic liposome complexation (DNA, RNA, SiRNA, antisense, protein ect.)

• Liposome characterization

• Particle size and distribution (DLS, qNano)

• Zeta potential/mobility (Brookhaven ZetaPALS)

• pH

• Osmolality

• Liposome phase transition (Microcal VP-DSC)

• Viscosity

• Scale-up and process development/optimization

• Analytical method development and support for API and excipients (lipids, sugar, Na, Cl etc.)

• HPLC, UHPLC-CAD, UV, fluorescence

• Formulation stability monitoring

• In vitro release method development and testing

• Liposome lyophilization

Other services:

• Protein denaturation temperature by DSC

• Characterization of nutritional liposomes

• Active potency (vitamin C, glutathione, lipoic acid, carnitine, zinc, magnesium, curcumin etc.) (HPLC)

• Liposome encapsulation efficiency (HPLC)

• Particle size by Malvern Zetasizer

• pH

• Viscosity of gels (polymer gels, liposome gels, etc.)

• Ultracentrifugation

• Fluorescent microscopy 

• Lyophylization/freeze dry