DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Sulfate Gradient (100nm)

Write a Review
Buy in bulk and save

DSPC/CHOL (55:45 mol/mol) Liposomes with Ammonium Gradient (100nm)

This product is prepared to the finest quality and shipped to you ready for drug loading. DSPC/CHO liposomes  with ammonium gradient is the formulator's choice for loading of weakly basic compounds, because it offers significantly improved drug retention and the ease of use in terms of process parameters such as loading temperature (60-70 deg C)  

One can use this liposomes as the placebo control for the drug loaded formulation or use the much cheaper plain DSPC liposomes as placebo control (F10203)



Product code: F20103A

Lipid composition: DSPC/CHOL (55:45 mol/mol)

Mean particle size: 100 nm (95 - 120 nm)

Lipid concentration: 60 mM (60 - 70 mM)

Hydration buffer (loading battery): 250 mM ammonium sulfate

External solution: 10% sucrose, 20mM NaPO4, pH 6.5 ± 0.2

Shelf-life: 6 months

Storage: 2-8 °C


DSPC: 18:0 PC,1,2-distearoyl-sn-glycero-3-phosphocholine

CHOL: cholesterol