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Binding/Interaction Studies

VP-ITC Isothermal Titration Calorimeter

We have years of experience of using VP-ITC to characterize binding/interactions of various type of compounds. 

Applications

  • Characterization of molecular interactions of small molecules, proteins, antibodies, nucleic acids, lipids and other biomolecules.
  • Characterization of binding of various molecules with drug delivery systems. 

Why VP-ITC?

  • Simultaneous determination of all binding parameters in a single experiment - information unobtainable from more limited binding assays
  • Directly measure sub-millimolar to nanomolar binding constants (102 to 109 M-1)
  • Application versatility:  Investigate any biomolecular interaction with high sensitivity
  • True in-solution technique: No labeling or immobilization required. No buffer restrictions. Easily handles turbid solutions
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