FormuMax has been providing custom-made formulations of liposomal doxorubicin HCl with various lipid compositions and particle sizes. There has been an increased demand of liposomal doxorubicin comparable to the commercial Doxil®. Now we are proudly naming our product, Doxoves®, and making it available to you at an affordable price.
Doxoves® is manufactured to high quality with consistent lot-lot characteristics, tight particle size distribution and high drug encapsulation efficiency. A high drug concentration of 4.0 mg/mL (40mM lipid) allows researchers to perform experiments at higher concentrations/doses. Doxoves® is comparable to the commercial product Doxil® in characteristics, stability and pharmacokinetics. Cryo-TEM studies have shown that the encapsulated doxorubicin forms the same type of rod-like structures as in Doxil®. A recent PK study of two batches of Doxoves® demonstrated an excellent PK profile with t1/2 of 30-40hr similar to that of Doxil®.
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Per request from customers, the 2.0mg/mL liposomal doxorubicin HCl is now available.
Doxoves ® (2.0mg/mL) - Cat#: F30204B-D2
Control liposomes: Cat#: F30204B-C2